Advances in the treatment of cancer have led to impressive improvements in the long-term prognosis of patients. Unfortunately, a major complication of these increasingly effective cancer therapies is reproductive failure resulting in men's temporary and even permanent infertility or sterility. We offer a range of technologies to help male cancer patients preserve their fertility. Reproductive Sciences Center has provided comprehensive fertility services to oncology patients for over 10 years.
Cancer treatment adversely affects sperm quality and can lead to infertility. We strongly encourage patients to freeze semen, preferably before initiation of cancer treatment to preserve fertility. Patients may have to undergo radiation, chemotherapy, or surgery as part of medical management. Each of these treatments has deleterious effects on sperm production or emission and can thus contribute to infertility. Certain types of cancer may also affect sperm quality even prior to the beginning of treatment.
Which patients benefit from sperm banking?
Recent studies have shown that semen from patients with many cancer types including testicular, seminoma, prostate, lymphoma, leukemia, and Hodgkin's can be successfully frozen, i.e. cryopreserved, even when sperm counts are low (as is true for about 50% of patients with testicular cancer).
When is the optimal time to bank sperm?
Due to potential genetic damage caused by chemotherapy, it is recommended that sperm be frozen before cancer treatment is initiated.
Can men with very low sperm counts or poor quality sperm successfully freeze sperm?
Yes, even for semen with the poorest quality and quantity of sperm, cryopreservation can still be an option when used with assisted reproductive technologies such as IVF and intracytoplasmic sperm injection (ICSI).
Can men with complete absence of sperm successfully cryopreserve sperm?
Yes, as long as at least one testis has zones of sperm production (spermatogenesis), sperm can be retrieved surgically from the epididymis (tubules adjacent to the testis where sperm is stored) or the testicular tissue and frozen for future use with ICSI.
Is it possible to predict who will later make use of sperm banking?
No, studies have shown it is not possible to reliably predict the fertility status for the individual patient after treatment. The probability of return of healthy sperm production varies according to age of patient at time of cancer treatment, treatment regimen used and type of disease.
Are there any risks associated with cryopreservation?
Yes, all tissue banking has inherent risks associated with loss of cell viability that can result from unforeseen equipment failure or environmental disaster. The Reproductive Sciences Center takes all reasonable precautions to avoid adverse outcomes, including test thaws on all sperm specimens and 24 hour monitoring of storage tanks.
How long can cryopreserved material be stored at Reproductive Sciences Center?
Specimens may be stored virtually indefinitely. Prolonged storage requires special arrangement with our center including current contact information. Patients are notified annually regarding number of vials of specimens in storage.
What is the genetic effect of cancer treatment on sperm?
Few studies have assessed the genetic effect of cancer treatment on sperm. Data so far from small patient populations show no evidence for a higher incidence of congenital malformations (birth defects) in children of former male cancer patients. However, there is evidence that during the period of recovery of sperm production (up to 2 years following treatment), there is a higher percentage of aneuploid sperm (genetically abnormal sperm with missing or extra chromosomes) which might result in higher rates of pregnancy loss, still birth and birth defects.
How and why should sperm DNA damage be assessed?
The structural organization of sperm DNA is vital for the proper functioning of the sperm. It is not clear whether cancer itself or the various cancer treatment regimens are capable of inducing structural changes in the sperm DNA. High levels of sperm DNA damage are associated with higher miscarriage rates and lower pregnancy rates in assisted fertilization techniques. The level of DNA integrity can be assessed in a sperm sample using the SCSA (sperm chromatin structure assay). We recommend the SCSA for all sperm specimens intended for use in fertility treatment.
More information for cancer patients is also available at FerileHope.
Our fertility specialists at The Reproductive Sciences Center, or RSC, are conveniently located in La Jolla California in San Diego County. We have worked hard to create and maintain our reputation as the first-rate San Diego fertility clinic and sciences center. RSC has become synonymous with comprehensive and successful female and male infertility treatment, egg donor programs and surrogacy options, in vitro fertilization, ICSI and more.
While we have provided services to hundreds of patients throughout the Temecula, Murrieta, La Jolla, Riverside,San Bernardino and Encinitas areas, we also help many people from across the United States, Europe, Australia , Asia, Africa and the Americas who make us their final destination for treatment with infertility in San Diego. We lead the area as one of the leading fertility centers in the world.
Our fertility center has long been established as having one of the highest fertility success rates in the world, and with more than 75 years of combined medical training, experience and ongoing continuing education, our fertility specialists set the bar for the industry. Our medical director and leading fertility doctor is one of the most well-respected experts in the world.
Successful fertility treatment in San Diego is only possible with the best fertility specialists and staff in OrangeCounty. We have been providing unsurpassed treatment for infertility in San Diego, including IVF (In Vitro Fertilization) and other San Diego fertility services in La Jolla for more than a decade.
Some of our successful options for fertility treatment in San Diego include natural fertility treatment, advanced fertility treatment, IUI (Intrauterine Insemination), San Diego In Vitro Fertilization (IVF), ICSI for severe male infertility, genetic testing, embryo donation, blastocyst transfers, assisted hatching, and more. We are the top professionals of fertility options for women with cancer and fertility options for men with cancer in San Diego as well.
You can find patient testimonials, interviews, news features and personal stories about our San Diego infertility treatment programs on the Internet by searching for: Dr. Wood, Dr. Sam Wood, Dr. Adams, La Jolla fertility clinic, San Diego egg donors, fertility San Diego, fertility specialists, IVF clinic, ICSI, male fertility clinic and fertility clinic.
Everybody makes a typo here and there, right? Searching the internet is no different. As a result, sometimes our patients find us by typing: ferility, inferility, fertility centre, fertilty, infertilty, micscarriage, miscarraige, fertiliy, infertiliy, fertilitydoctors, clinicfertility, ferlity, and inferlity. Doctor Wood sometimes has his name spelled as Dr. Woods.